Established in 1943 for the protection of migratory birds, Santa Ana National Wildlife Refuge is positioned along an east-west and north-south juncture of two major migratory routes for many species of birds. It is also at the northern-most point for many species whose range extends south into Central and South America. The refuge is right in the middle of all this biological diversity, which is what makes this 2,088-acre parcel the ‘jewel of the National Wildlife Refuge System.’ Though small in size, Santa Ana offers visitors an opportunity to see birds, butterflies and many other species not found anywhere else in the United States beyond deep South Texas.